Emulsions as vehicles for the controlled release of astaxanthin in topical application / Michał Dymek, Elżbieta Sikora // W: EYEC monograph : 9th European Young Engineers Conference [Dokument elektroniczny]. ... więcej

Emulsions as vehicles for the controlled release of astaxanthin in topical application / Michał Dymek, Elżbieta Sikora // W: EYEC monograph : 9th European Young Engineers Conference [Dokument elektroniczny]. – Warsaw : Faculty of Chemical and Process Engineering. Warsaw University of Technology, 2021. – S. 35-41 : fot., tab., wykr. – Tryb dostępu: https://www.eyec.ichip.pw.edu.pl/?page_id=2995. – Oznaczenie ref./art.: 6.2. – Bibliogr. 36 poz., Abstr. – Rozszerzony abstr. ref. zamieszczono również na s. 177. – Mat. konf.: 9th EYEC, Warszawa, 19-21.04.2021. – ISBN 978-83-936575-9-9

In the work, the antioxidant activity of astaxanthin (AST) and the influence of the base formulation on the kinetics of AST release were studied. Three stable O/W ASTloaded emulsions, differing in the ... więcej

In the work, the antioxidant activity of astaxanthin (AST) and the influence of the base formulation on the kinetics of AST release were studied. Three stable O/W ASTloaded emulsions, differing in the internal phase droplet size (12.7 μm (E1), 3.8 μm (E2), 3.2 μm (E3)) and a nanoemulsion (0.13 μm, NE) were prepared. The results confirmed very strong antioxidant activity of AST. The emulsion internal phase droplet size did not significantly affect the AST release. The amount of released AST was respectively: 13.60% (E1), 11.42% (E2), 9.45% (E3), 9.71% (NE). The best fit to experimental data was obtained using the Higuchi model for emulsions and the Korsmeyer-Peppas model for NE. The results show that the AST release process is limited by the diffusion through carriers and the prepared O/W emulsions can be used as vehicles for the controlled delivery of AST to the skin.